Nonalcoholic fatty liver disease is a common complication of hemochromatosis.
Hemochromatosis is a medical condition characterized by an excessive buildup of iron in the body. It can lead to iron accumulation in various organs, including the liver.
A buildup of iron in the liver can damage the liver cells and cause inflammation, resulting in fatty liver disease.
Other organs that can be affected by hemochromatosis
- pancreas
- heart
- joints
- skin
- pituitary gland
The liver is sensitive to a buildup of iron. Although excess iron from hemochromatosis may not cause obvious symptoms initially, significant scarring or damage to the liver can result in the following:
- tiredness and weakness
- loss of appetite
- weight loss
- itchy skin
- tenderness or pain around the liver (upper right quadrant of your stomach)
- yellowing of the eyes and skin (jaundice)
- an overall feeling of unwellness
See a doctor if you experience any of the above symptoms.
Nonalcoholic fatty liver disease caused by hemochromatosis is primarily treated through:
- phlebotomy: a process of removing blood from your body
- chelation: a process that removes iron from your blood
Lifestyle modifications can also help, especially weight loss through diet and exercise, and avoiding alcohol.
Medications, such as statins, may also be used to manage cholesterol in people with nonalcoholic fatty liver disease.
The outlook for people with nonalcoholic fatty liver disease caused by hemochromatosis can be positive if the condition is diagnosed and treated early. This means working with a doctor to reduce iron levels and implementing lifestyle changes to prevent further damage to the liver.
However, the outlook is less positive if severe scarring of the liver has already occurred at the time of diagnosis.
A liver transplant is an option for people with end stage liver disease caused by hemochromatosis.